While the Affini Compact's technology circa 25XX Terran Common Era is in all fields is far beyond Terran, (or indeed any other civilization's) technology, there are still several limits that even Affini Compact science has not or perhaps cannot breach.
While the affini have some access to Inertialess Drives on especially their larger ships, true artificial gravity is either infeasible, impossible, or inferior in some way to conventional alternatives. In most stories, artificial ‘gravity’ is achieved by rotating ring habitats.
Affini jump drives are faster, longer ranged, more efficient, faster to charge, and ‘quieter’ than Terran jump drives by orders of magnitude. Affini have reasonably trivial FTL comms through some method (frequent, small, dispersed subspace ansible relays?), while Terrans were only beginning to experiment with FTL comms by the time official first contact with the Affini Compact was established. Affini FTL comms, while extremely fast, are still bounded by some speed. It would take years or longer for an arbitrary piece of information on one side of Affini Compact space to propagate to the other via their highly decentralized informational database scheme.
Perhaps the pinnacle of Affini science & technology is their medical & biotech, especially in regards to their own bodies. The modern affini is near infinitely adaptable, durable, strong, and possess numerous senses & abilities beyond what the historical affini possessed. This self modification is so well substantial that the modern affini is effectively biologically immortal via the bloom system.
Xenobiotech is also extremely advanced, though even affini science will take an immense amount of time to fully cure death in a species (if ever they do). Xenobiotech is mostly focused on xenodrugs & haustoric implant science. An implanted individual can safely experience more extreme situations, as well as undergo more extreme modifications than an unimplanted individual. It generally takes no more than 5 terran years for a Cotyledon program to conclude with any new xeno species.
Conventional weaponry outclasses the vast majority of other civilizations' efforts by far; and is complemented with cognitohazardous ‘weaponry’ embedded into most affini ships, stations, equipment, and individuals